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Chapter 1: Cluster Origin of Solvent Fea... > NANOBIOTECHNLOGY: SELF-ASSEMBLING CY... - Pg. 28

Cluster Origin of Solvent Features nanotechnologies (Balogh 2009). Nanomaterials are a type of drug carriers with promising applica- tion. Progress was achieved in making drugs own characteristics of targeted and controlled release via nanotechnologies. Liu et al. (2010) addressed nanodrug capability on targeting to cells, penetrat- ing via epicyte, controlled release and security resulting from using. Gai et al. (2010) reported synthesis­characterization­application in con- trolled drug release for monodisperse core­shell- structured Fe 3 O 4 @nSiO 2 @mSiO 2 @NaYF 4 : Yb 3+ , Er 3+ /Tm 3+ NCs with mesoporous, up-conversion luminescent and magnetic properties. The NCs show typical ordered mesoporous characteristics and a monodisperse spherical morphology, with narrow size distribution. They exhibit high mag- netization and unique up-conversion emission under 980nm laser excitation, even after loading with drug molecules. Drug release tests suggest that multifunctional NCs present a controlled 2005; Sweeney et al., 2004), proteins (ferritin) (Douglas & Stark, 2000; Kramer et al., 2004; Li et al., 2003; Meldrum et al., 1992), heat-shock proteins (Flenniken et al., 2003, 2005; Klem et al., 2005) and viral capsids. The latter were used as scaffolds for (in)organic material assembly, selective attachment­presentation of chemo­bio- moieties and building blocks for 1/2/3D-array construction (Arora & Kirshenbaum, 2004; Bittner, 2005; Douglas & Young, 2006; Flynn et al., 2003; Singh et al., 2006). Efforts were devoted to structures design­preparation­char- acterization on sub-100nm scale and their use as novel functional devices (Whitesides, 2005). The NTs are attractive as potential building blocks for various applications in fields, e.g., catalysis, drug delivery, optics, electronics, chemotherapy and transmembrane transport, because their physi- cal­chemical properties are tunable via control of their size­shape (Martin & Kohli, 2003). Although