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As we have alluded to before, managing permissions directly anywhere other than the site root is usually a bad idea. Every content object in a Plone site is subject to security, and will in most cases inherit permission settings from its parent. If we start making special settings in particular folders, we will quickly lose control.
However, if settings are always acquired, how can we restrict access to particular folders or prevent authors from editing published content whilst still giving them rights to work on items in a draft state? The answer to both of these problems is workflow.