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Since the NetBackup software runs in a networked environment, it is susceptible to vulnerabilities such as denial of service attacks. To prevent these situations from happening, the following best practices are recommended by Veritas, which is now Symantec:
Allow administrative access to privileged users only
Allow remote access only from trusted servers
Apply the latest patches
Install NetBackup behind a firewall
Ensure virus protection is running on the servers
Monitor network traffic for malicious activity
Block external access to the default ports used by NetBackup
NetBackup server and clients should face towards the internal network