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To install the anti-spam agents on a Hub Transport server, navigate to the C:\Program Files\Microsoft\Exchange Server\Scripts directory (on a default installation) in Exchange Management Shell and run the install-antispamagents.ps1 PowerShell executable script.
After installation, you can view and configure the anti-spam agents on the Anti-spam tab under the Organization Configuration | Hub Transport node in Exchange Management Console. (Close and reopen the console if the Anti-spam tab does not appear.)