Free Trial

Safari Books Online is a digital library providing on-demand subscription access to thousands of learning resources.


  • Create BookmarkCreate Bookmark
  • Create Note or TagCreate Note or Tag
  • PrintPrint
Share this Page URL
Help

15. Gene silencing—ancient immune response and a versatile mechanism of cont...

15. Gene silencing—ancient immune response and a versatile mechanism of control over the fate of foreign nucleic acids

RNA interference (RNAi) is an epigenetic mechanism of homology-dependent gene silencing that is induced by double-stranded RNA. Since its discovery in plants, RNAi has been observed in a variety of organisms ranging from fungi to animals. RNAi has evolved as a process involved in defense against viruses, protection against transposons, the regulation of chromatin structure, control over gene expression, specification of cell identity, and the regulation of development of multicellular organisms. This chapter describes in detail the RNAi process, the mechanism of virus-induced gene silencing (VIGS), and viRNA (virus-derived siRNA) function.


  

You are currently reading a PREVIEW of this book.

                                                                                                                    

Get instant access to over $1 million worth of books and videos.

  

Start a Free Trial


  
  • Safari Books Online
  • Create BookmarkCreate Bookmark
  • Create Note or TagCreate Note or Tag
  • PrintPrint