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If you’re shooting landscapes, you’re probably shooting at around dusk and around dawn, and if that’s the case, you’re probably shooting on a tripod, and if that’s the case (see how I’m stringing this whole case together?), then you need to be shooting at the lowest ISO your camera will allow (usually ISO 200 on most Nikon dSLRs, or ISO 100 on Canons). The reason why is you’ll get the sharpest, most noise-free, best quality images at your lowest ISO, and because you’re on a tripod, you don’t need to raise your ISO above that sweet spot (remember, raising your ISO is usually for hand-holding in low light; you’re not hand-holding, you’re on a tripod, so go for the ultimate in quality).