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The Web Content Accessibility Guidelines (WCAG 2.0) has been very carefully designed to be technologically agnostic, and I trust you will see the common sense in them when you are building your web sites and applications. Building accessible stuff that works is a very nuanced area. As I mentioned previously, you will have to balance real-world application of both the code and these guidelines in a way that is practical. Accessibility is not theoretical, mystical, or ethereal.
The needs of people with disabilities are very real and these guidelines are just that—guidelines and not a standard. They are meant to be informative and instructive, with the net result being that you have more accessible and usable interfaces.